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Semaglutide is contraindicated in patients with: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Common Adverse Effects According to clinical trial data, gastrointestinal effects are most frequently reported: nausea, vomiting, diarrhea, constipation, and abdominal discomfort

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Eli Lilly which makes Mounjaro released another tirzepatide medication called Zepbound, which was FDA-approved to treat weight loss in 2023

Lillys testing of products obtained from compounding pharmacies, medspas and telehealth networks found significant levels of an impurity that results from a chemical reaction between tirzepatide and B12, according to the letter and a scientific manuscript on the testing process shared with Reuters